Methylation, smoking, and reduced lung function
نویسندگان
چکیده
منابع مشابه
Reduced Lung Function and Progression to Prediabetes: A Prospective Study
Objective: Prediabetes is a state that people have blood glucose levels higher than normal but still not in diabetes range. There is a close relationship between impaired lung function and diabetes mellitus (DM). Reduced lung function can be present before the clinical evidence of diabetes or insulin resistance. Materials and Methods: The total number of subjects in this longitudinal study was ...
متن کاملSmoking, lung function, and body weight.
In a cross-sectional study of steelworkers aged 45-55 years, smokers (n = 105; mean weight 76.1 kg) were found to weigh significantly less than non-smokers (n = 54; 81.6 kg) and ex-smokers (n = 51; 82.6 kg). The lower weight of smokers was attributable to a group with airflow obstruction (n = 37; forced expiratory volume in one second/vital capacity (FEV1/VC) less than 66%), who weighed less (4...
متن کاملSmoking women and their lung function tests.
Smoking amongst women has become significant as the number of smoking women is increasing gradually in this developing society. It affects the lungs to produce Chronic Obstructive Pulmonary Disease (COPD). Present study was conducted over 100 smoker's women and 100 non-smoker women in the age group of 30-40 Years. Three Lung Function Tests--FEVI, FVC and PEFR were employed to all smoking and no...
متن کاملThe interactions between cigarette smoking and reduced lung function on systemic inflammation.
BACKGROUND Low-grade systemic inflammation is commonly observed in conditions associated with reduced FEV(1). Active cigarette smoking, which is a leading risk factor for decreased FEV(1), can also independently induce systemic inflammation. STUDY OBJECTIVES To determine the independent contributions of active cigarette smoking and reduced FEV(1) (as well as their potential interactions) on s...
متن کاملAberrant promoter methylation of p16 and MGMT genes in lung tumors from smoking and never-smoking lung cancer patients.
Aberrant methylation in gene promoter regions leads to transcriptional inactivation of cancer-related genes and plays an integral role in tumorigenesis. This alteration has been investigated in lung tumors primarily from smokers, whereas only a few studies involved never-smokers. Here, we applied methylation-specific polymerase chain reaction to compare the frequencies of the methylated promote...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2019
ISSN: 0903-1936,1399-3003
DOI: 10.1183/13993003.00920-2019